NBEO Systemic Disease Practice Exam 2025 - Free Systemic Disease Practice Questions and Study Guide

Question: 1 / 560

What are the three components of Virchow's Triad?

Venous stasis, vascular injury, hypocoagulable state

Venous stasis, hypercoagulable state, endothelial injury

Virchow's Triad is a model that describes the three broad categories of factors that contribute to the development of venous thrombosis. The correct components of this triad consist of venous stasis, a hypercoagulable state, and endothelial injury.

Venous stasis refers to the slowing or pooling of blood in the veins, which can occur due to prolonged immobility, certain medical conditions, or external compression of veins. This stagnation increases the likelihood of clot formation.

The hypercoagulable state is characterized by an increased tendency of the blood to clot, which can result from genetic conditions, medications, or other underlying health issues that alter the coagulation pathway.

Endothelial injury involves damage to the vascular endothelium, which can occur due to trauma, inflammation, or other pathological processes. This injury exposes the underlying tissue and initiates the clotting cascade, further promoting thrombosis.

Understanding these components is crucial for clinical practice as they help in identifying patients at risk for thrombosis and guide prevention strategies.

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Arterial injury, venous thrombus, stasis

Hypercoagulable state, vascular injury, thrombus

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